承担项目: (1)基于基因工程单链抗体的食品中小分子化学污染物快速检测压电免疫传感器研究。编号:31171700,国家自然科学基金面上项目,2012.1-2015.12,项目负责人,65万,在研。 (2)基于纳米增效分子印迹膜的农药多残留高通量快速检测传感器微阵列研究。编号:30972056,国家自然科学基金面上项目,2010.01-2012.12,项目负责人,32万,已结题。 (3)基于糖基功能化分子印迹聚合物的细菌毒素检测生物传感器。编号:30911140278,国家自然科学基金中韩合作与交流项目,2009.06-2011.05,8万,项目负责人,已结题。 (4)农产品中痕量环境内分泌干扰物残留检测的纳米增效分子印迹仿生传感技术研究,编号:30700535,国家自然科学基金青年科学基金项目,2008.01-2010.12,18万,项目负责人,已结题。 (5)加工食品中生物危害物多元识别与控制技术,编号:2012AA101604,国家863项目,2012.1-2015.12,64万,第六参加人,在研。 (6)基于基因工程单链抗体的重要真菌毒素检测研究,编号:2007AA10Z430,国家863专题课题,2007.10-2010.10,15万,第二参加人(课题组副组长),已结题。 (7)基于纳米增效分子印迹膜的痕量重要真菌毒素快速检测仿生传感系统。编号:BS2009NY001,山东省优秀中青年科学家科研奖励基金,2009.12-2012.12,项目负责人,已结题。 (8)纳米增效分子印迹膜为感受器的农药多残留高通量快速检测传感芯片。 编号:2010GNC10960,山东省科技发展计划,2010.1-2012.12,项目负责人,已结题。 科研论文: (1) Wei Xu, Su Liu, Jinghua Yu, Min Cui, Jie Li, Yuna Guo, Hongzhi Wang,Jiadong Huang*. An ultrasensitive HRP labeled competitive aptasensor for oxytetracycline detection based on graphene oxide-polyaniline composites as the signal amplifiers. RSC Advances, 2014, 4: 10273-10279.(SCI,IF=2.562) (2) Xia Sun, Falan Li, Guanghui Shen,Jiadong Huang*, Xiangyou Wang*. Aptasensor based on the synergistic contributions of chitosan-gold nanoparticles, grapheme-gold nanoparticles and multi-walled carbon nanotubescobalt phthalocyanine nanocomposites for kanamycin detection. Analyst, 2014, 139: 299-308.(SCI,IF=3.969) (3) Wenjing Lian, Su Liu, Jinghua Yu, Jie Li, Min Cui, Wei Xu,Jiadong Huang*. Electrochemical sensor using neomycin-imprinted film as recognition element based on chitosan-silver nanoparticles/graphene- multiwalled carbon nanotubes composites modified electrode. Biosensors and Bioelectronics, 2013, 44: 70-76.(SCI,IF=5.437) (4) Min Cui, Su Liu, Wenjing Lian, Jie Li, Wei Xu,Jiadong Huang*. A molecularly-imprinted electrochemical sensor based on a grapheme-Prussian blue composite-modified glassy carbon electrode for the detection of butylated hydroxyanisole in foodstuffs. Analyst, 2013, 138: 5949-5955.(SCI,IF=3.969) (5) Jie Li, Su Liu, Jinghua Yu, Wenjing Lian, Min Cui, Wei Xu,Jiadong Huang*. Electrochemical immunosensor based on grapheme-polyanilinecomposites and carboxylated graphene oxide for estradiol detection. Sensors & Actuators: B. Chemical, 2013, 188: 99-105.(SCI,IF=3.535) (6) Wenjing Lian, Su Liu, Jinghua Yu, Jie Li, Min Cui, Wei Xu,Jiadong Huang*. Determination of Oxytetracycline with a Gold Electrode Modified by Chitosan-Multiwalled Carbon Nanotube Multilayer Films and Gold Nanoparticles. Analytical Letters, 2013, 46: 1117-1131.(SCI,IF=0.965) (7) Wenjing Lian, Su Liu, Jinghua Yu, Xianrong Xing, Jie Li, Min Cui,Jiadong Huang*. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. Biosensors and Bioelectronics, 2012, 38: 163-169.(SCI, IF=5.361) (8) Su Liu, Xianrong Xing, Jinghua Yu, Wenjing Lian, Jie Li, Min Cui,Jiadong Huang*. A novel label-free electrochemical aptasensor based on graphene-polyaniline composite film for dopamine determination. Biosensors and Bioelectronics, 2012, 36: 186-191.(SCI, IF=5.361) (9) Xianrong Xing, Su Liu, Jinghua Yu, Wenjing Lian,Jiadong Huang*. Electrochemical sensor based on molecularly imprinted film at polypyrrole-sulfonated graphene/hyaluronic acid-multiwalled carbon nanotubes modified electrode for determination of tryptamine. Biosensors and Bioelectronics, 2012, 31: 277-283.(SCI, IF=5.361) (10) Su Liu, Qing Lin, Xiuming Zhang, Xiaorui He, Xianrong Xing, Wenjing Lian, Jie Li, Min Cui,Jiadong Huang*. Electrochemical immunosensor based on mesoporous nanocomposites and HRP-functionalizednanoparticles bioconjugates for sensitivity enhanced detection of diethylstilbestrol. Sensors and Actuators B: Chemical, 2012, 166-167: 562-568.(SCI, IF=3.368) 专利发明: (1)糖基功能化细菌毒素分子印迹膜基片及其制备方法和应用,发明专利,专利号:ZL200910018460.6,第一位。 (2)检测细菌毒素的纳米增效糖基功能化分子印迹膜电极的制备方法及应用,发明专利,专利号:ZL200910018459.3,第一位。 (3)检测细菌毒素的糖基功能化分子印迹膜电极的制备方法及应用,发明专利,专利号:ZL200910018461.0,第一位。 (4)一种糖基功能化细菌毒素分子印迹聚合物、制备方法及应用,发明专利,专利号:ZL200910020308.1,第一位。 (5)痕量真菌毒素分子印迹柱制备方法及应用,发明专利,专利号:ZL2008100166995,第一位。 (6)纳米增效糖基功能化细菌毒素分子印迹膜基片及其制备方法和应用,发明专利,专利号:200910018456.X,第一位。 (7)一种糖基功能化细菌毒素分子印迹柱的制备方法及应用,发明专利,专利号:ZL 200910018457.4,第一位。 (8)一种检测细菌毒素的糖基功能化分子印迹膜电极,实用新型专利,专利号:ZL200920239018.1,第一位。 (9)纳米增效的检测细菌毒素的糖基功能化分子印迹膜电极,实用新型专利,专利号:ZL200920239017.7,第一位。 (10)用于真菌毒素检测的分子印迹膜电极,实用新型专利,专利号:ZL2008200217460,第一位。 (11)用于环境内分泌干扰物检测的分子印迹膜电极,实用新型专利,专利号:ZL200820021748X,第一位。 获奖情况: (1)分子识别生物活性界面的基础研究,天津市人民政府,天津市自然科学奖,三等奖,第五位,2012。 (2)基于新型发光试剂和传感器设计的高选择性发光分析研究,山东省教育厅,山东高等学校优秀科研成果奖,一等奖,第三位,2010。 |