主要科研成果与奖励（主持项目、获奖、著作、代表性论文） 主持项目： 1. 山东省自然科学基金青年基金，丝状真菌LaeA催化组蛋白甲基化的精细构架与作用机制，2020.07-2022.06，主持； 2. 中国博士后科学基金面上资助，丝状真菌LaeA催化组蛋白甲基化的精细构架与作用机制，2020.09-2021.08，主持。 代表性论文： 1. Zhang X., Qu Y., Qin Y. 2016. Expression and chromatin structures of cellulolytic enzyme gene regulated by heterochromatin protein 1. Biotechnol for Biofuels. 9:206. 2. Zhang X., Zhu Y., Bao L., Gao L., Yao G., Li Y., Yang Z., Li Z., Zhong Y., Li F., Yin H., Qu Y., Qin Y. 2016. Putative methyltransferase LaeA and transcription factor CreA are necessary for proper asexual development and controlling secondary metabolic gene cluster expression. Fungal Genet Biol. 94:32-46. 3. Zhang, X., Li M., Zhu Y., Yang L., Li Y., Qu J., Wang L., Zhao J., Qu Y., Qin Y.. 2020. Penicillium oxalicum putative methyltransferase Mtr23B has similarities and differences with LaeA in regulating conidium development and glycoside hydrolase gene expression. Fungal Genet Biol. 143, 103445. 4. Li Y., Zheng X., Zhang X., Bao L., Zhu Y., Qu Y., Zhao J., Qin Y.. 2016. The Different Roles of Penicillium oxalicum LaeA in the Production of Extracellular Cellulase and β-xylosidase. Front Microbiol. 22;7:2091. 5. Pan Y., Gao L., Zhang X., Qin Y., Liu G., Qu Y.. 2019. The Role of Cross-Pathway Control Regulator CpcA in the Growth and Extracellular Enzyme Production of Penicillium oxalicum. Current microbiology. 77(11). 6. Kang W., Ji X., Zhang X., Tang D., Feng Q.. 2019. Persistent Exposure to Fusobacterium nucleatum Triggers Chemokine/Cytokine Release and Inhibits the Proliferation and Osteogenic Differentiation Capabilities of Human Gingiva-Derived Mesenchymal Stem Cells. Frontiers in cellular and infection microbiology. 9: 429. 7. Shi Z., Han C., Zhang X., Tian L., Wang L.. Novel synergistic mechanism for lignocellulose degradation by a thermophilic filamentous fungus and a thermophilic actinobacterium based on functional proteomics. Front Microbiol. 2020 Sep 11;11:539438. |
